TL;DR

To be under 50 mg of residual caffeine at an 11 PM bedtime, have your last serving (typical) of Pre-Workout (typical serving) (254 mg) by 11:15 AM (11:15). The math uses the median 5-hour caffeine half-life; individual half-lives range from about 2 to 12 hours.

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Pre-Workout (typical serving) Last-Call Times by Bedtime

Latest time to finish one serving (typical) of Pre-Workout (typical serving) (254 mg of caffeine) and still be under 50 mg of residual caffeine at bedtime, assuming the median 5-hour half-life. Your personal half-life may sit anywhere in the 2 to 12 hour range.

BedtimeLast call for Pre-Workout (typical serving)Residual at bedtime
9:00 PM (21:00)9:15 AM (09:15)~50 mg
10:00 PM (22:00)10:15 AM (10:15)~50 mg
11:00 PM (23:00)11:15 AM (11:15)~50 mg
12:00 AM (00:00, midnight)12:15 PM (12:15)~50 mg

Clearance Time by Serving Size

How long each serving of Pre-Workout (typical serving) needs before bed to drop under 50 mg:

ServingCaffeineTime needed before bed
1 serving (typical)254 mg11 h 44 min

Source: caffeine figures from Jagim et al. 2019, Common Ingredient Profiles of Multi-Ingredient Pre-Workout Supplements (Nutrients), accessed 2026-06-11. Values can vary by batch, location, and preparation; check the label or the source for the latest figures.

How the Math Works

Caffeine leaves your body by exponential decay. With the median 5-hour half-life, the 254 mg in one serving (typical) of Pre-Workout (typical serving) falls to 127 mg after 5 hours and 64 mg after 10 hours. To get under 50 mg, the level where caffeine stops measurably delaying sleep for most people, it needs about 11 h 44 min of clearance time. Subtract that from your bedtime and you get the last-call times above, rounded down to the nearest 15 minutes.

The big caveat: the 5-hour figure is a median. Depending on CYP1A2 genetics, medications, smoking, and pregnancy, real half-lives run from about 2 to 12 hours. If caffeine reliably keeps you up, treat these times as too generous and move your personal cutoff earlier, or model your own curve in the caffeine half-life calculator.

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Frequently Asked Questions

There is no magic number, but around 50 mg of circulating caffeine the alerting effect fades for most people, which makes it a practical sleep-ready marker (the same one the Unbuzz app and our half-life calculator use). For Pre-Workout (typical serving), that means the 254 mg in one serving (typical) needs about 11 h 44 min of decay to get under that mark. Caffeine-sensitive sleepers may need to aim lower; the calculator lets you change the threshold.
These times assume the median 5-hour half-life, but CYP1A2 genetics, oral contraceptives, pregnancy, some medications, and age stretch individual half-lives across roughly 2 to 12 hours. At an 8-hour half-life, the 254 mg in one serving (typical) of Pre-Workout (typical serving) needs about 18 h 46 min to clear instead of 11 h 44 min, so a slow metabolizer should stop hours earlier than this table suggests. The caffeine half-life calculator adjusts the curve to your profile.
Residual caffeine adds up. Two servings (508 mg total) need about 16 h 44 min to clear under 50 mg, noticeably longer than one. Log each serving in the half-life calculator or the Unbuzz app to see the combined curve.
Standard exponential decay: residual = dose x 0.5^(hours / 5), using the drink's sourced caffeine content (254 mg per 1 serving (typical), per Jagim et al. 2019, Common Ingredient Profiles of Multi-Ingredient Pre-Workout Supplements (Nutrients)) and the median 5-hour half-life. The last call is the latest time that leaves under 50 mg at bedtime, rounded down to 15 minutes so the rounding never works against your sleep.

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Medical Disclaimer: Caffeine values are approximate figures from the cited public sources. Actual content may vary by batch, location, and preparation, and caffeine metabolism varies widely between individuals. This page is for informational purposes only and is not medical advice. The FDA guideline for healthy adults is up to 400 mg of caffeine per day; the recommended limit during pregnancy is 200 mg per day. Consult a healthcare professional for personalized guidance.